Uridine 5 '- monophosphate disodium salt is an organic compound with the chemical formula c9h13o9n2pna2 · H2O. It is the disodium salt of uridine 5' - monophosphate. It can also become uridine monophosphate disodium salt. It is a colorless or white crystalline powder without impurities visible to normal vision; Odorless, tasteless and hygroscopic Store under shading and sealing. Soluble in water (41g / 100ml), slightly soluble in methanol, insoluble in ethanol. It is an important component of synthetic RNA; It's a flavoring agent.
Uridine monophosphate disodium (UMP) can be used in three aspects. First, it can only be used as a flavoring agent. Although the products in our laboratory are chemicals, the final product of uridine monophosphate disodium salt is edible, so it can be added to milk as a flavoring, The main reason for adding milk is that it can increase the amount of nucleoside acid and make it close to the composition of human milk to the greatest extent. As we all know, for infants and young children, human milk contains a variety of trace elements. The absorption of trace elements can enhance the physical resistance of infants and young children and increase the resistance to the environment. Therefore, adding it to milk can protect the health of infants and young children. The second aspect of use is that uridine 5 '- monophosphate can be used as an auxiliary drug for liver disease. It is recorded in the relevant literature that uridine 5' - monophosphate has been used as medicine to a certain extent. Its component is a nucleotide, which is combined with nucleotide and glucose, which can reduce the burden of the liver in the human digestive system, so it is added to the drug as an API. The third use is related to the second use, but it more clearly shows that uridine monophosphate disodium salt can be used as a drug intermediate to produce nucleic acid drugs. Since it is involved in drugs as a drug intermediate and in the digestive system, it can also be used as a component of health products and health food. The fourth aspect is chemistry. Uridine 5 monophosphate disodium can be used as a biochemical reagent, which can be used to manufacture drugs such as uridine triphosphate (UTP), polyadenyluria, and fluoroiron.
The scientific researchers in our laboratory specially sorted out the industrialized preparation method of uridine 5 monophosphate disodium: in this experiment, the tributylamine salt of UTP uses carbodiimide condensation agent to obtain cyclic triphosphate, and then synthesize P, P di (uridine 5 'tetraphosphate) with the tributylamine salt of the ump. The reaction solution directly uses the salt of organic acid to form salt crystallization without concentration, After dissociation, no concentration shrinkage is required after gradient elution with anion exchange resin. After desalination and dehydration by membrane filtration, high-purity P, P di (uridine 5 'tetraphosphate) sodium salt has been obtained The method of the invention can prepare P, P di (uridine 5 'tetraphosphate) sodium salt to meet the medicinal requirements in large quantities.
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